sc 29338 grp94 sirna santa cruz biotech (Santa Cruz Biotechnology)
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sc 29338 grp94 sirna santa cruz biotech
Sc 29338 Grp94 Sirna Santa Cruz Biotech, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/grp94+sirna/GRP+94+siRNA/pm36471805-196-129-132
Average 93 stars, based on 7 article reviews
Sc 29338 Grp94 Sirna Santa Cruz Biotech, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 7 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/grp94+sirna/GRP+94+siRNA/pm36471805-196-129-132
Average 93 stars, based on 7 article reviews
sc 29338 grp94 sirna santa cruz biotech - by Bioz Stars,
2026-09
93/100 stars
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1) Product Images from "BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1."
Article Title: BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1.
Journal: iScience
doi: 10.1016/j.isci.2022.105626
Figure Legend Snippet: Figure 3. Depleting UPR components is lethal to the BRCA1-def cancer cells (A) MDA-MB-436 (BRCA1-def or +), HCC1937 BRCA1-def and SUMPT149 BRCA1-def breast cancer cells were transfected with control, CypB, IRE1, GRP94, HSP70, BiP, PERK or DERL1 siRNA and assessed for cell survival. (B) HCC1937 BRCA1+, MDA-MB-231, MCF7, and MCF10A cells were transfected with CypB siRNA and assessed for cell survival. (C) MDA-MB-436 (+ or def) and HCC1937 (+ or def) breast cancer cells were transfected with control, CypB-A or CypB-B siRNA. Top, western blot analysis. Bottom, clonal cell survival analysis. (D) MDA-MB-436 BRCA1-def cells were transfected with either (i) pCMV vector and siRNA control, (ii) PPIB/pCMV and siRNA control, (iii) pCMV control and CypB 30UTR siRNA or (iv) PPIB/pCMV and CypB 30UTR siRNA for cell survival and Western blot analysis. N.S. = not significant. F-CypB = Flag-tagged cyclophilin B. Bar charts are the summary of the quantitative analysis of the colony forming units (CFU) from each siRNA transfection experiment. Data are displayed as mean G SD. P values were calculated by Student’s two-tailed, unpaired t-test. See also Figures S7 and S8.
Techniques Used: Transfection, Control, Western Blot, Plasmid Preparation, Two Tailed Test
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